To celebrate acts of kindness around the country, Allergan, Inc. (NYSE: AGN), the maker of BOTOX® Cosmetic (onabotulinumtoxinA), has announced the "BOTOX® Cosmetic My Expressions of Kindness" charitable campaign. Allergan is asking everyone who is treated with BOTOX® Cosmetic, or is considering talking to their physician about treatment, to post acts of kindness online to help raise up to a quarter of a million dollars for three deserving charities: Make It Right, Dress for Success and Children's Action Network. The online fundraising campaign is being spearheaded by television personality, long-time volunteer and BOTOX® Cosmetic advocate Didiayer Snyder, who is joined by fellow BOTOX® Cosmetic fans Emmy®-nominated actress and singer Vanessa Williams, best-selling author Vicki Iovine, Oscar®-nominated actress Virginia Madsen and five-time gold medalist Nadia Comaneci as campaign ambassadors.
People are asked to get involved and show their support by visiting the campaign Web site at ExpressKindnessCampaign.com to complete a "My Expressions of Kindness" profile. Upon completion, a $25 donation will be automatically generated and each person will have the opportunity to choose whether it will benefit Make It Right, Dress for Success or Children's Action Network. The "My Expressions of Kindness" profiles completed by each of the campaign ambassadors who have pledged their support to one of the charity partners is also posted on the Web site. Other social media fundraising activities include Facebook and Twitter.
Mrs. Snyder is supporting Make It Right, which builds safe, green and affordable homes for working families in New Orleans Lower 9th Ward who lost everything in Hurricane Katrina. Ms. Williams, who spearheaded the 2009 "BOTOX® Cosmetic: Express Success" campaign with Dress for Success, returns this year and is joined by Ms. Iovine in support of Dress for Success, which helps disadvantaged women express success in the workforce by providing them with the tools they need to succeed in work and life. Ms. Madsen and Ms. Comaneci are supporting Children's Action Network, which finds homes for foster children who are waiting for an adoptive family and works to improve outcomes for children in foster care. The organizations were selected based on research that shows women are drawn to causes that support their core emotional values – underserved communities, family and health.
"I'm thrilled to be spearheading the 'BOTOX® Cosmetic My Expressions of Kindness' charitable campaign because it is a way to give back to the community by supporting causes that are important to many men and women," said Mrs. Snyder. "Allergan asked me to become involved because they knew I dedicated a significant amount of time to supporting those less fortunate and that I was a big fan of BOTOX® Cosmetic. Now people who are treated with or thinking about talking to their doctor about being treated with BOTOX® Cosmetic to temporarily reduce the appearance of the '11' – those moderate to severe vertical lines between the brows that can give your face a tired and stressed look – can spread kindness online to help raise much-needed funds for Make It Right, Dress for Success and the Children's Action Network. It's fun, easy and a great way to support those in need."
"With this campaign, we are delighted BOTOX® Cosmetic can serve as a champion for causes that consumers care about and can help raise awareness and support for organizations that serve those less fortunate," said Robert Grant, president of Allergan Medical, a division of Allergan, Inc. "Since the approval of BOTOX® Cosmetic eight years ago, we have spearheaded consumer education campaigns that provide education about the product. Now, we are combining these efforts with charitable support and are joining hands with long-time supporters including Virginia Madsen, Vanessa Williams, Vicki Iovine and Nadia Comaneci – plus work with Didiayer Snyder our new ambassador – to support causes important to both them and the people who choose to talk to their doctor about being treated with our products."
For more information about the "BOTOX® Cosmetic My Expressions of Kindness" campaign, please visit www.ExpressKindnessCampaign.com. For more information about BOTOX® Cosmetic, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
Showing posts with label allergan. Show all posts
Showing posts with label allergan. Show all posts
Wednesday, July 28, 2010
Wednesday, February 17, 2010
Save Money on Allergan Botox With Brilliant Distinctions Program
The Brilliant Distinctions™ Program is an exciting new program that offers a multitude of great rewards when you receive BOTOX® Cosmetic treatments! If you are a regular Botox user, this program will save you money. Think of it as a "frequent flyer" program for Botox, where you receive 200 points ($25 dollars) per Botox treatment. You can use your points right away, or wait and combine them in the future for a bigger discount. Earn points for Botox purchases, then redeem the points towards Botox, Juvederm, or Latisse.
Receive special offers and exclusive invitations. Enjoy all the program has to offer!
Exclusive offers and invitations
Insider access to special events
Treatment reminders, newsletters, and special offers. The latest information, tips, and news from the Brilliant Distinctions™ Program
Earn Points For BOTOX® Cosmetic Treatments
Redeem coupons for a number of great rewards, including dollars off BOTOX® Cosmetic, Juvederm products, and Latisse. Earn a higher return per point as you accumulate more points -- which means the more you participate in the program, the greater the rewards!
An activation code is required to begin! Call any one of our Derma Health Institute locations below to schedule your appointment and receive your code.
Derma Health Institute
Ahwatukee/Phoenix
Phone: 480-460-1505
Derma Health Institute
Chandler/Tempe
Phone: 480-730-9000
Derma Health Institute
Mesa/Gilbert
Phone: 480-539-0777
Derma Health Institute
Paradise Valley/Scottsdale
Phone: 480-991-7900
http://www.dermahealthinstitute.com
Receive special offers and exclusive invitations. Enjoy all the program has to offer!
Exclusive offers and invitations
Insider access to special events
Treatment reminders, newsletters, and special offers. The latest information, tips, and news from the Brilliant Distinctions™ Program
Earn Points For BOTOX® Cosmetic Treatments
Redeem coupons for a number of great rewards, including dollars off BOTOX® Cosmetic, Juvederm products, and Latisse. Earn a higher return per point as you accumulate more points -- which means the more you participate in the program, the greater the rewards!
An activation code is required to begin! Call any one of our Derma Health Institute locations below to schedule your appointment and receive your code.
Derma Health Institute
Ahwatukee/Phoenix
Phone: 480-460-1505
Derma Health Institute
Chandler/Tempe
Phone: 480-730-9000
Derma Health Institute
Mesa/Gilbert
Phone: 480-539-0777
Derma Health Institute
Paradise Valley/Scottsdale
Phone: 480-991-7900
http://www.dermahealthinstitute.com
Increase in Botox Sales May be an Indication of Economic Faith
(Phoenix, AZ) – In fourth quarter 2009 Derma Health Institute saw a significant increase in injectables like Botox and Dysport as well as facial fillers like Juvederm and Perlane. A recent survey conducted by MEDACorp uncovered similar results, reporting these procedures had increased nationwide for the first time since the economic downturn began in 2007. Findings like this may indicate consumers are beginning to feel a sense of economic optimism.
“Last year our Botox and Dysport business increased by 115% and our Juvederm and Perlane business increased 89%,” said Trish Gulbranson, Derma Health Institute owner. “This is a positive sign that patients feel like the market is starting to turn around.”
In this economic climate companies like Allergan, the maker of Botox, have also increased their customer service programs. They recently started a promotion called Brilliant Distinctions, which encourages customers to sign up for an email list and get up to $50 in credit towards their first Botox visit at Derma Health Institute. Patients then receive emails every 4-6 months reminding them to make their next Botox appointment. According to Gulbranson customers absolutely love this VIP service.
“The nice thing about Botox and Juvederm is that they’re a quick fix, minimally invasive and provide instant results. We’ve seen a decrease in the cost of both these products in the last few years. An average woman can get Botox for about $250 and get rid of that ‘angry line’ between their eyes. Juvederm treatments have also decreased in cost to from $600 a syringe to $399. With these, patients come out looking years younger, rejuvenated and relaxed.”
Derma Health Institute has earned the highest certification level awarded by Allergan, Black Diamond. As one of the largest providers of Botox and Juvederm in the nation, they have an immense amount of experience and results with these procedures.
For more information on Botox, Juvederm or other filler options, contact Derma Health Institute in Mesa/Gilbert at (480) 539-0777, Chandler/Tempe at (480) 730-9000, Ahwatukee/Phoenix at (480) 460-1505 or Paradise Valley/Scottsdale at (480) 991-7900.
http://www.dermahealthinstitute.com
“Last year our Botox and Dysport business increased by 115% and our Juvederm and Perlane business increased 89%,” said Trish Gulbranson, Derma Health Institute owner. “This is a positive sign that patients feel like the market is starting to turn around.”
In this economic climate companies like Allergan, the maker of Botox, have also increased their customer service programs. They recently started a promotion called Brilliant Distinctions, which encourages customers to sign up for an email list and get up to $50 in credit towards their first Botox visit at Derma Health Institute. Patients then receive emails every 4-6 months reminding them to make their next Botox appointment. According to Gulbranson customers absolutely love this VIP service.
“The nice thing about Botox and Juvederm is that they’re a quick fix, minimally invasive and provide instant results. We’ve seen a decrease in the cost of both these products in the last few years. An average woman can get Botox for about $250 and get rid of that ‘angry line’ between their eyes. Juvederm treatments have also decreased in cost to from $600 a syringe to $399. With these, patients come out looking years younger, rejuvenated and relaxed.”
Derma Health Institute has earned the highest certification level awarded by Allergan, Black Diamond. As one of the largest providers of Botox and Juvederm in the nation, they have an immense amount of experience and results with these procedures.
For more information on Botox, Juvederm or other filler options, contact Derma Health Institute in Mesa/Gilbert at (480) 539-0777, Chandler/Tempe at (480) 730-9000, Ahwatukee/Phoenix at (480) 460-1505 or Paradise Valley/Scottsdale at (480) 991-7900.
http://www.dermahealthinstitute.com
Monday, August 31, 2009
Ramp Up Your Looks With Botox Treatments
By Nick Messe
You may have just discovered that, to your horror, you have sprouted frown lines and wrinkles on your once youthful face, and crow's feet near your eyes. Now all you can think of is getting rid of those impertinent insults to your good looks.
For more information about Botox at Derma Health Institute, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
There is something you can do to reduce signs of aging. It is called Botox, which may sound a little frightening at first. You may have heard that it is the cosmetic form of botulinum toxin. That word that reminds us of botulism, which certainly has unpleasant connotations.
Botox, however, is approved by the Food and Drug Administration (FDA), and has steadily gained popularity as the most performed cosmetic procedure the world over. Indeed, this toxin has the ability to relax the muscles that cause wrinkles.
The medication is injected into a frown or wrinkle crease, blocking nerve impulses and smoothing out the skin. It used to be that the only way to minimize the wrinkles on aging, sagging skin, was to go under the knife.
This, of course, was a rather drastic procedure. It was one that involved a lot of healing while the patient hid behind closed doors and then big hats and sunglasses. To top it off, the surgery would need to be repeated in a few short years.
Botox, on the other hand, is administered in pleasantly appointed medical spas by the capable hands of board certified Nurse Practitioners. These facilities are safe and clean and devoted to a patient's complete physical and mental comfort.
Be sure to take your time and ask lots of questions at your initial evaluation consultation. The nurse will explain that while there is some discomfort, it will be brief and low on a scale of one to ten. If you are particularly sensitive, the practitioner can use a cold pack or anesthetic cream.
You will gradually see a plumping up of your creases in two to three days, culminating in about seven days. Plumping can remain for a period of four to six months. The beauty of this treatment is that it is gradual. Your friends will notice that you look rested and fresher, but they will not suspect that you had something done unless you tell them.
When you notice the wrinkles coming back, you can simply have another session, or let the frown lines and crow's feet return. We'll bet that you will opt for a tune-up because Botox is fast, safe, and subtle.
For more information about Botox at Derma Health Institute, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
About the Author
Nick Messe is the founder and president of Lead Frog LLC. Find out more about Botox Treatment Chicago. Visit chicago laser hair removal and botox Chicago specialists.
Article Source: http://EzineArticles.com/?expert=Nick_Messe
You may have just discovered that, to your horror, you have sprouted frown lines and wrinkles on your once youthful face, and crow's feet near your eyes. Now all you can think of is getting rid of those impertinent insults to your good looks.
For more information about Botox at Derma Health Institute, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
There is something you can do to reduce signs of aging. It is called Botox, which may sound a little frightening at first. You may have heard that it is the cosmetic form of botulinum toxin. That word that reminds us of botulism, which certainly has unpleasant connotations.
Botox, however, is approved by the Food and Drug Administration (FDA), and has steadily gained popularity as the most performed cosmetic procedure the world over. Indeed, this toxin has the ability to relax the muscles that cause wrinkles.
The medication is injected into a frown or wrinkle crease, blocking nerve impulses and smoothing out the skin. It used to be that the only way to minimize the wrinkles on aging, sagging skin, was to go under the knife.
This, of course, was a rather drastic procedure. It was one that involved a lot of healing while the patient hid behind closed doors and then big hats and sunglasses. To top it off, the surgery would need to be repeated in a few short years.
Botox, on the other hand, is administered in pleasantly appointed medical spas by the capable hands of board certified Nurse Practitioners. These facilities are safe and clean and devoted to a patient's complete physical and mental comfort.
Be sure to take your time and ask lots of questions at your initial evaluation consultation. The nurse will explain that while there is some discomfort, it will be brief and low on a scale of one to ten. If you are particularly sensitive, the practitioner can use a cold pack or anesthetic cream.
You will gradually see a plumping up of your creases in two to three days, culminating in about seven days. Plumping can remain for a period of four to six months. The beauty of this treatment is that it is gradual. Your friends will notice that you look rested and fresher, but they will not suspect that you had something done unless you tell them.
When you notice the wrinkles coming back, you can simply have another session, or let the frown lines and crow's feet return. We'll bet that you will opt for a tune-up because Botox is fast, safe, and subtle.
For more information about Botox at Derma Health Institute, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
About the Author
Nick Messe is the founder and president of Lead Frog LLC. Find out more about Botox Treatment Chicago. Visit chicago laser hair removal and botox Chicago specialists.
Article Source: http://EzineArticles.com/?expert=Nick_Messe
Wednesday, July 29, 2009
Allergan Announces BOTOX Cosmetic Express Success Charity
IRVINE, Calif., May 15 /PRNewswire/ -- In honor of working women who have helped make BOTOX(R) Cosmetic (Botulinum Toxin Type A) the most popular physician-administered aesthetic treatment for the last seven years, Allergan, Inc. (NYSE: AGN) has announced the "BOTOX(R) Cosmetic: Express Success" charitable education campaign. Spearheaded by actress and singer Vanessa Williams, the campaign will benefit the not-for-profit Dress for Success, an organization that helps disadvantaged women succeed in the workforce, through a $250,000 donation from Allergan. The donation will support the organization in its efforts to promote the economic independence of disadvantaged women by providing professional attire, a network of support and the career development tools to help women thrive in work and in life.
http://www.dermahealthinstitute.com
"Dress for Success is about more than providing business attire to women in need. Our mission is to change women's lives by enabling them to express success and confidence in their professional endeavors," said Joi Gordon, CEO of Dress for Success. "We're excited to partner with Allergan and Vanessa Williams to raise awareness of Dress for Success."
As part of the donation to Dress for Success, up to $50,000 of the total $250,000 donation will be generated through an online drive, with Allergan donating $2 to the organization on behalf of each of the first 25,000 people who visit and register on the campaign Web site, ExpressSuccessCampaign.com. When pledging support on the Web site, people also can enter to win a trip for two to New York City to have lunch with Vanessa Williams, read Vanessa's personal blog as well as get interview and workplace tips.
In addition to the donation, the "BOTOX(R) Cosmetic: Express Success" campaign includes a series of educational events featuring campaign ambassador, Vanessa Williams, Dress for Success CEO Joi Gordon and an aesthetic-specialty physician. The events will take place in select markets across the country where consumers will be able to support Dress for Success by donating nearly new professional attire as a cost of entry, while learning about fast and simple tips for working women, including treatment with BOTOX(R) Cosmetic.
"As a working woman and actress, I know how important it is to 'look the part' when interviewing for a new position or in any professional setting. It's no secret that I receive BOTOX(R) Cosmetic treatments, which is a quick procedure that reduces the two frown lines in between my brows that look like an '11' and give me a tired or stressed appearance," said Ms. Williams. "For me, putting my best face forward means finding ways to help other women express their own success, personally and professionally. That's why I'm so excited to be involved with the 'BOTOX(R) Cosmetic: Express Success' campaign benefiting Dress for Success, which has helped more than 500,000 women prepare for, find and keep the job that ultimately leads to financial independence. There is truly no better time to get involved than now, so I ask all women to join our efforts by pledging their support online, joining us at our local events and participating in our New York City launch event."
Vanessa Williams will host the "BOTOX(R) Cosmetic: Express Success" campaign launch event with Allergan and Dress for Success on June 30 in New York City's Union Square. The event includes a celebrity "Rack Relay Race" and clothing drive. The public is invited to join Vanessa in the race by donating nearly new professional clothing and registering to race on ExpressSuccessCampaign.com. The first 100 people to pre-register online and participate in the "Rack Relay Race" will receive a certificate for a physician consultation and, if appropriate, a complimentary BOTOX(R) Cosmetic treatment from a licensed and trained aesthetic-specialty physician. The winning "Rack Relay Race" team also will win an opportunity to have lunch with Vanessa Williams in New York City.
Additional information about the launch and local events is available on the campaign Web site which also features an inspiring animated video featuring Vanessa Williams and three Dress for Success graduates directed by Dex Deboree, a highly acclaimed Grammy(R)-award nominee.
"We are pleased to launch the 'BOTOX(R) Cosmetic: Express Success' campaign on behalf of the women who have helped make BOTOX(R) Cosmetic the most popular physician administered treatment over the past seven years," said Robert Grant, president of Allergan Medical, a division of Allergan, Inc. "During this time, Allergan has developed many programs to educate women about the product, especially the importance of seeing a licensed and trained physician. Through this campaign, Allergan also will be realizing the important philanthropic goal of helping disadvantaged women around the country fulfill their professional potential and express their success. It's a first of its kind campaign for BOTOX(R) Cosmetic and we are proud to be partnering with both Dress for Success and Vanessa Williams on this important mission."
For more information about BOTOX(R) Cosmetic and the "BOTOX(R) Cosmetic: Express Success" campaign, please visit www.ExpressSuccessCampaign.com.
About BOTOX(R) Cosmetic
BOTOX(R) Cosmetic (Botulinum Toxin Type A) was approved by the U.S. Food and Drug Administration (FDA) in 2002 for the temporary improvement in the appearance of moderate to severe glabellar lines (the vertical "frown lines" between the eyebrows) in adult women and men ages 18 to 65. The glabellar lines, which often look like the number "11," can have a negative effect on one's overall facial appearance by creating a sad, angry, or tired impression.
BOTOX(R) Cosmetic has been ranked as the number one physician-administered, aesthetic injectable treatment(2) and 11.8 million treatment sessions with BOTOX(R) Cosmetic have been recorded in the United States alone.(3) High patient satisfaction rates following treatment with BOTOX(R) Cosmetic have been well established with 97 percent of patients indicating satisfaction with the product, according to a survey of approximately 1,000 patients conducted by the research arm of the American Society for Aesthetic Plastic Surgery (ASAPS).(4)
Important BOTOX(R) Cosmetic (Botulinum Toxin Type A) Information
BOTOX(R) Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18 to 65.
Important Safety Information
BOTOX(R) Cosmetic injections should not be given to people who have an infection where the physician proposes to inject. They should not be given to people who are known to be sensitive to any ingredient in BOTOX(R) Cosmetic.
Serious heart problems and serious allergic reactions have been reported rarely. If you think you are having an allergic reaction or other reactions, such as difficulty swallowing, speaking, or breathing, call your doctor immediately. The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness, and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious side effects.
The FDA on April 30, 2009, in its update to the early communication sent in 2008, gave the following recommendations:
* Understand that dosage strength (potency) expressed in "Units" or "U" are different among the botulinum toxin products; clinical doses expressed in units are not interchangeable from one botulinum toxin product to another. * Be alert to and educate patients and caregivers about potential adverse events due to distant spread of botulinum toxin effects following local injections including: unexpected loss of strength or muscle weakness, hoarseness or trouble talking (dysphonia), trouble saying words clearly (dysarthria), loss of bladder control, trouble breathing, trouble swallowing, double vision, blurred vision and drooping eyelids. * Understand that these adverse events have been reported as early as several hours and as late as several weeks after treatment. * Advise patients to seek immediate medical attention if they develop any of these symptoms.
About Dress for Success
Dress for Success is an international not-for-profit organization that promotes the economic independence of disadvantaged women by providing professional attire, a network of support and the career development tools to help women thrive in work and in life. Since starting operations in 1997, Dress for Success has expanded to more than 90 cities in the U.S., Canada, Mexico, the Netherlands, New Zealand, Poland, the UK and the West Indies. To date, Dress for Success has helped more than 500,000 women work towards self-sufficiency. Visit http://www.dressforsuccess.org to learn more.
About Vanessa Williams:
Vanessa Williams has achieved success in every area of entertainment, including the worlds of music, theatre, film and television. She has sold millions of albums, earning multiple Grammy(R) Award nominations and countless other awards and honors. She has starred in numerous films, television and Broadway productions and has won or been nominated for the Emmy(R), Golden Globe(R) and Screen Actors Guild(R) awards and has won two NAACP Image Awards for her role as the deliciously wicked Wilhelmina Slater on the hit ABC series, "Ugly Betty." Concord Records will release her 13th album, "The Real Thing" in June and she recently appeared in the box-office hit, "Hannah Montana: The Movie."
About Allergan, Inc.
Founded in 1950, Allergan, Inc., with headquarters in Irvine, California, is a multi-specialty health care company that discovers, develops and commercializes innovative pharmaceuticals, biologics and medical devices that enable people to live life to its greatest potential - to see more clearly, move more freely, express themselves more fully. The Company employs more than 8,000 people worldwide operates state-of-the-art R&D facilities and world-class manufacturing plants. In addition to its discovery-to-development research organization, Allergan has global marketing and sales capabilities with a presence in more than 100 countries.
http://www.dermahealthinstitute.com
http://www.dermahealthinstitute.com
"Dress for Success is about more than providing business attire to women in need. Our mission is to change women's lives by enabling them to express success and confidence in their professional endeavors," said Joi Gordon, CEO of Dress for Success. "We're excited to partner with Allergan and Vanessa Williams to raise awareness of Dress for Success."
As part of the donation to Dress for Success, up to $50,000 of the total $250,000 donation will be generated through an online drive, with Allergan donating $2 to the organization on behalf of each of the first 25,000 people who visit and register on the campaign Web site, ExpressSuccessCampaign.com. When pledging support on the Web site, people also can enter to win a trip for two to New York City to have lunch with Vanessa Williams, read Vanessa's personal blog as well as get interview and workplace tips.
In addition to the donation, the "BOTOX(R) Cosmetic: Express Success" campaign includes a series of educational events featuring campaign ambassador, Vanessa Williams, Dress for Success CEO Joi Gordon and an aesthetic-specialty physician. The events will take place in select markets across the country where consumers will be able to support Dress for Success by donating nearly new professional attire as a cost of entry, while learning about fast and simple tips for working women, including treatment with BOTOX(R) Cosmetic.
"As a working woman and actress, I know how important it is to 'look the part' when interviewing for a new position or in any professional setting. It's no secret that I receive BOTOX(R) Cosmetic treatments, which is a quick procedure that reduces the two frown lines in between my brows that look like an '11' and give me a tired or stressed appearance," said Ms. Williams. "For me, putting my best face forward means finding ways to help other women express their own success, personally and professionally. That's why I'm so excited to be involved with the 'BOTOX(R) Cosmetic: Express Success' campaign benefiting Dress for Success, which has helped more than 500,000 women prepare for, find and keep the job that ultimately leads to financial independence. There is truly no better time to get involved than now, so I ask all women to join our efforts by pledging their support online, joining us at our local events and participating in our New York City launch event."
Vanessa Williams will host the "BOTOX(R) Cosmetic: Express Success" campaign launch event with Allergan and Dress for Success on June 30 in New York City's Union Square. The event includes a celebrity "Rack Relay Race" and clothing drive. The public is invited to join Vanessa in the race by donating nearly new professional clothing and registering to race on ExpressSuccessCampaign.com. The first 100 people to pre-register online and participate in the "Rack Relay Race" will receive a certificate for a physician consultation and, if appropriate, a complimentary BOTOX(R) Cosmetic treatment from a licensed and trained aesthetic-specialty physician. The winning "Rack Relay Race" team also will win an opportunity to have lunch with Vanessa Williams in New York City.
Additional information about the launch and local events is available on the campaign Web site which also features an inspiring animated video featuring Vanessa Williams and three Dress for Success graduates directed by Dex Deboree, a highly acclaimed Grammy(R)-award nominee.
"We are pleased to launch the 'BOTOX(R) Cosmetic: Express Success' campaign on behalf of the women who have helped make BOTOX(R) Cosmetic the most popular physician administered treatment over the past seven years," said Robert Grant, president of Allergan Medical, a division of Allergan, Inc. "During this time, Allergan has developed many programs to educate women about the product, especially the importance of seeing a licensed and trained physician. Through this campaign, Allergan also will be realizing the important philanthropic goal of helping disadvantaged women around the country fulfill their professional potential and express their success. It's a first of its kind campaign for BOTOX(R) Cosmetic and we are proud to be partnering with both Dress for Success and Vanessa Williams on this important mission."
For more information about BOTOX(R) Cosmetic and the "BOTOX(R) Cosmetic: Express Success" campaign, please visit www.ExpressSuccessCampaign.com.
About BOTOX(R) Cosmetic
BOTOX(R) Cosmetic (Botulinum Toxin Type A) was approved by the U.S. Food and Drug Administration (FDA) in 2002 for the temporary improvement in the appearance of moderate to severe glabellar lines (the vertical "frown lines" between the eyebrows) in adult women and men ages 18 to 65. The glabellar lines, which often look like the number "11," can have a negative effect on one's overall facial appearance by creating a sad, angry, or tired impression.
BOTOX(R) Cosmetic has been ranked as the number one physician-administered, aesthetic injectable treatment(2) and 11.8 million treatment sessions with BOTOX(R) Cosmetic have been recorded in the United States alone.(3) High patient satisfaction rates following treatment with BOTOX(R) Cosmetic have been well established with 97 percent of patients indicating satisfaction with the product, according to a survey of approximately 1,000 patients conducted by the research arm of the American Society for Aesthetic Plastic Surgery (ASAPS).(4)
Important BOTOX(R) Cosmetic (Botulinum Toxin Type A) Information
BOTOX(R) Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18 to 65.
Important Safety Information
BOTOX(R) Cosmetic injections should not be given to people who have an infection where the physician proposes to inject. They should not be given to people who are known to be sensitive to any ingredient in BOTOX(R) Cosmetic.
Serious heart problems and serious allergic reactions have been reported rarely. If you think you are having an allergic reaction or other reactions, such as difficulty swallowing, speaking, or breathing, call your doctor immediately. The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness, and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious side effects.
The FDA on April 30, 2009, in its update to the early communication sent in 2008, gave the following recommendations:
* Understand that dosage strength (potency) expressed in "Units" or "U" are different among the botulinum toxin products; clinical doses expressed in units are not interchangeable from one botulinum toxin product to another. * Be alert to and educate patients and caregivers about potential adverse events due to distant spread of botulinum toxin effects following local injections including: unexpected loss of strength or muscle weakness, hoarseness or trouble talking (dysphonia), trouble saying words clearly (dysarthria), loss of bladder control, trouble breathing, trouble swallowing, double vision, blurred vision and drooping eyelids. * Understand that these adverse events have been reported as early as several hours and as late as several weeks after treatment. * Advise patients to seek immediate medical attention if they develop any of these symptoms.
About Dress for Success
Dress for Success is an international not-for-profit organization that promotes the economic independence of disadvantaged women by providing professional attire, a network of support and the career development tools to help women thrive in work and in life. Since starting operations in 1997, Dress for Success has expanded to more than 90 cities in the U.S., Canada, Mexico, the Netherlands, New Zealand, Poland, the UK and the West Indies. To date, Dress for Success has helped more than 500,000 women work towards self-sufficiency. Visit http://www.dressforsuccess.org to learn more.
About Vanessa Williams:
Vanessa Williams has achieved success in every area of entertainment, including the worlds of music, theatre, film and television. She has sold millions of albums, earning multiple Grammy(R) Award nominations and countless other awards and honors. She has starred in numerous films, television and Broadway productions and has won or been nominated for the Emmy(R), Golden Globe(R) and Screen Actors Guild(R) awards and has won two NAACP Image Awards for her role as the deliciously wicked Wilhelmina Slater on the hit ABC series, "Ugly Betty." Concord Records will release her 13th album, "The Real Thing" in June and she recently appeared in the box-office hit, "Hannah Montana: The Movie."
About Allergan, Inc.
Founded in 1950, Allergan, Inc., with headquarters in Irvine, California, is a multi-specialty health care company that discovers, develops and commercializes innovative pharmaceuticals, biologics and medical devices that enable people to live life to its greatest potential - to see more clearly, move more freely, express themselves more fully. The Company employs more than 8,000 people worldwide operates state-of-the-art R&D facilities and world-class manufacturing plants. In addition to its discovery-to-development research organization, Allergan has global marketing and sales capabilities with a presence in more than 100 countries.
http://www.dermahealthinstitute.com
Friday, May 22, 2009
DermaSkin Clinic Warns Against Rogue Botox Providers
Mar 23, 2009 – “We are trying to make Botox more accessible for people who had not considered trying the procedure before. Nowadays, Botox is not limited to just Hollywood stars, and since the nineties the number of clinics has mushroomed. Although Botox has been used for other conditions in the past such as muscle spasms, cranial nerve disorders and ophthalmic spasm, when the FDA finally approved Botox in the early 90s to be used to treat facial wrinkles, the popularity of the toxin rose tremendously.” Says Dr. Sid Gautam of DermaSkin.co.uk (http://www.DermaSkin.co.uk)
For more information about Botox treatments at Derma Health Institute, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
He added that, “On any given day, thousands of Botox treatments are carried out in the UK and the US, but with the increase in the number of rogue traders, one must be sure of the credentials of the service provider. It is truly a wonder of science and technology. Botox has been found to be very effective at removing and reducing forehead wrinkle lines and other facial asymmetries. In fact, after a few Botox treatments clients see that their facial lines actually weaken and their skin takes on a more permanently smooth appearance."
Speaking on the move, Dr. Sid Gautam said, "Botulinum toxin is extremely potent, but Botox injections are diluted to the extent that they are very safe to use clinically and have been proven to be effective and safe in the right hands." (http://www.DermaSkin.co.uk)
For more information about Botox treatments at Derma Health Institute, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
For more information about Botox treatments at Derma Health Institute, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
He added that, “On any given day, thousands of Botox treatments are carried out in the UK and the US, but with the increase in the number of rogue traders, one must be sure of the credentials of the service provider. It is truly a wonder of science and technology. Botox has been found to be very effective at removing and reducing forehead wrinkle lines and other facial asymmetries. In fact, after a few Botox treatments clients see that their facial lines actually weaken and their skin takes on a more permanently smooth appearance."
Speaking on the move, Dr. Sid Gautam said, "Botulinum toxin is extremely potent, but Botox injections are diluted to the extent that they are very safe to use clinically and have been proven to be effective and safe in the right hands." (http://www.DermaSkin.co.uk)
For more information about Botox treatments at Derma Health Institute, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
Number of Women Over Sixty Using Botox is Increasing
MANCHESTER, England, April 25 /PRNewswire/ -A NEW trend in beauty has been seen by staff at Transform, the UK's leading plastic surgeons and non-surgical treatments: the rise of Botox Grannies.
More and more women over 60 are having non-surgical treatments including Botox, dermal fillers and skin peels and treatments, as well as plastic surgery such as breast implants and facelifts.
For more information about Botox at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
Encouraged by their daughters and the increasing high profiles and media coverage of amazing looking celebrities who are in their 50s, 60s and 70s, such as Joan Collins, Jane Seymour and Lulu, UK's Botox Grannies are driving a new demand for non-surgical cosmetic treatments.
Plastic Surgery and Botox Grannies
Transform Plastic Surgery, the UK's leading cosmetic surgeons and non-surgical providers, has noticed the number of Botox Grannies double in the last two years and claims that the over 60s market now accounts for over a sixth of all Botox injections carried out across cosmetic treatment clinics nationwide.
Disposable Income & Lifestyle
This group of recently retired have more disposable income than ever before, and, coupled with the increasing profile and popularity of plastic surgery and non-surgical treatments, many women are wondering why they shouldn't treat themselves and ensure they look good in their twilight years.
Celebrity Influence
Recent celebrity photos of Helen Mirren looking amazing in her red bikini have also fuelled the demand for both non-surgical and surgical treatments. Other figures released by Transform Cosmetic Surgery show that the number of breast implants, breast augmentations and face lifts among this generation has increased by a third on the previous year.
Botox & Confidence
Gwen Davies, non-surgical manager at Transform Cosmetic Surgery, explains the benefits of Botox for the over 60s: "There are two types of older women who want to have Botox and dermal fillers: those who have been having treatments subtly for the past 15 years and just want to look fresh and age slowly, and those who are just discovering the benefits. Botox is not a magic cure for deep wrinkles but it can soften lines around the eyes and mouth which can have a fantastic freshening effect on the face.
"Women over 60 who are having treatments tend to be more discreet about what they have done in comparison to their younger counter parts. Women who have looked after themselves and already have good skin would benefit from Botox the most. A small amount of Botox can have a wonderful effect on their appearance and self-confidence."
Shami Thomas from Transform Cosmetic Surgery states: "The number of procedures carried out is continuously rising; even during the credit crunch people still want to look good and are sill happy to spend money on their appearance. People are now living longer than ever before and there are so many high profile older actresses that women want the same effects at home.
"Many older celebrities are also very open about their treatments that they have had done so it is only helping to increase the confidence of potential patients about becoming a British Botox Granny."
Editors Notes
8% of all Transform's Botox patients were over 60 in 2007 and 14% of all Transform's Botox patients were over 60 in 2008
Breast implants and breast augmentations for the over 60s increased by 31% between 2007 and 2008
Face lifts for the over 60s increased by 35% between 2007 and 2008
Transform Cosmetic Surgery Group is Britain's largest and most popular cosmetic surgery group network with over 30 years experience and 26 clinics across the UK
Transform offers a comprehensive and extensive post-operative care programme, which is included in the cost of the treatments. The programme serves to ensure that recovery is as swift and problem free as possible
Transform works with highly qualified and specialist cosmetic surgeons and nursing staff
Transform is a member of the Covenant Healthcare Group
http://www.transforminglives.co.uk
http://www.transforminglives.co.uk/footer/press_enquiries.aspx
For more information about Botox at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
For more information please call Sasha Blake or Emma Trimble @ Brazen PR on 0161 923 4994 or email Sasha@brazenpr.com or emmat@brazenpr.com
This press release was issued through 24-7PressRelease.com. For further information, visit http://www.24-7pressrelease.com.
More and more women over 60 are having non-surgical treatments including Botox, dermal fillers and skin peels and treatments, as well as plastic surgery such as breast implants and facelifts.
For more information about Botox at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
Encouraged by their daughters and the increasing high profiles and media coverage of amazing looking celebrities who are in their 50s, 60s and 70s, such as Joan Collins, Jane Seymour and Lulu, UK's Botox Grannies are driving a new demand for non-surgical cosmetic treatments.
Plastic Surgery and Botox Grannies
Transform Plastic Surgery, the UK's leading cosmetic surgeons and non-surgical providers, has noticed the number of Botox Grannies double in the last two years and claims that the over 60s market now accounts for over a sixth of all Botox injections carried out across cosmetic treatment clinics nationwide.
Disposable Income & Lifestyle
This group of recently retired have more disposable income than ever before, and, coupled with the increasing profile and popularity of plastic surgery and non-surgical treatments, many women are wondering why they shouldn't treat themselves and ensure they look good in their twilight years.
Celebrity Influence
Recent celebrity photos of Helen Mirren looking amazing in her red bikini have also fuelled the demand for both non-surgical and surgical treatments. Other figures released by Transform Cosmetic Surgery show that the number of breast implants, breast augmentations and face lifts among this generation has increased by a third on the previous year.
Botox & Confidence
Gwen Davies, non-surgical manager at Transform Cosmetic Surgery, explains the benefits of Botox for the over 60s: "There are two types of older women who want to have Botox and dermal fillers: those who have been having treatments subtly for the past 15 years and just want to look fresh and age slowly, and those who are just discovering the benefits. Botox is not a magic cure for deep wrinkles but it can soften lines around the eyes and mouth which can have a fantastic freshening effect on the face.
"Women over 60 who are having treatments tend to be more discreet about what they have done in comparison to their younger counter parts. Women who have looked after themselves and already have good skin would benefit from Botox the most. A small amount of Botox can have a wonderful effect on their appearance and self-confidence."
Shami Thomas from Transform Cosmetic Surgery states: "The number of procedures carried out is continuously rising; even during the credit crunch people still want to look good and are sill happy to spend money on their appearance. People are now living longer than ever before and there are so many high profile older actresses that women want the same effects at home.
"Many older celebrities are also very open about their treatments that they have had done so it is only helping to increase the confidence of potential patients about becoming a British Botox Granny."
Editors Notes
8% of all Transform's Botox patients were over 60 in 2007 and 14% of all Transform's Botox patients were over 60 in 2008
Breast implants and breast augmentations for the over 60s increased by 31% between 2007 and 2008
Face lifts for the over 60s increased by 35% between 2007 and 2008
Transform Cosmetic Surgery Group is Britain's largest and most popular cosmetic surgery group network with over 30 years experience and 26 clinics across the UK
Transform offers a comprehensive and extensive post-operative care programme, which is included in the cost of the treatments. The programme serves to ensure that recovery is as swift and problem free as possible
Transform works with highly qualified and specialist cosmetic surgeons and nursing staff
Transform is a member of the Covenant Healthcare Group
http://www.transforminglives.co.uk
http://www.transforminglives.co.uk/footer/press_enquiries.aspx
For more information about Botox at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
For more information please call Sasha Blake or Emma Trimble @ Brazen PR on 0161 923 4994 or email Sasha@brazenpr.com or emmat@brazenpr.com
This press release was issued through 24-7PressRelease.com. For further information, visit http://www.24-7pressrelease.com.
Allergan Announces BOTOX Cosmetic Express Success Charity
IRVINE, Calif., May 15 /PRNewswire/ -- In honor of working women who have helped make BOTOX(R) Cosmetic (Botulinum Toxin Type A) the most popular physician-administered aesthetic treatment for the last seven years, Allergan, Inc. (NYSE: AGN) has announced the "BOTOX(R) Cosmetic: Express Success" charitable education campaign. Spearheaded by actress and singer Vanessa Williams, the campaign will benefit the not-for-profit Dress for Success, an organization that helps disadvantaged women succeed in the workforce, through a $250,000 donation from Allergan. The donation will support the organization in its efforts to promote the economic independence of disadvantaged women by providing professional attire, a network of support and the career development tools to help women thrive in work and in life.
For more information about the Botox at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
"Dress for Success is about more than providing business attire to women in need. Our mission is to change women's lives by enabling them to express success and confidence in their professional endeavors," said Joi Gordon, CEO of Dress for Success. "We're excited to partner with Allergan and Vanessa Williams to raise awareness of Dress for Success."
As part of the donation to Dress for Success, up to $50,000 of the total $250,000 donation will be generated through an online drive, with Allergan donating $2 to the organization on behalf of each of the first 25,000 people who visit and register on the campaign Web site, ExpressSuccessCampaign.com. When pledging support on the Web site, people also can enter to win a trip for two to New York City to have lunch with Vanessa Williams, read Vanessa's personal blog as well as get interview and workplace tips.
In addition to the donation, the "BOTOX(R) Cosmetic: Express Success" campaign includes a series of educational events featuring campaign ambassador, Vanessa Williams, Dress for Success CEO Joi Gordon and an aesthetic-specialty physician. The events will take place in select markets across the country where consumers will be able to support Dress for Success by donating nearly new professional attire as a cost of entry, while learning about fast and simple tips for working women, including treatment with BOTOX(R) Cosmetic.
"As a working woman and actress, I know how important it is to 'look the part' when interviewing for a new position or in any professional setting. It's no secret that I receive BOTOX(R) Cosmetic treatments, which is a quick procedure that reduces the two frown lines in between my brows that look like an '11' and give me a tired or stressed appearance," said Ms. Williams. "For me, putting my best face forward means finding ways to help other women express their own success, personally and professionally. That's why I'm so excited to be involved with the 'BOTOX(R) Cosmetic: Express Success' campaign benefiting Dress for Success, which has helped more than 500,000 women prepare for, find and keep the job that ultimately leads to financial independence. There is truly no better time to get involved than now, so I ask all women to join our efforts by pledging their support online, joining us at our local events and participating in our New York City launch event."
Vanessa Williams will host the "BOTOX(R) Cosmetic: Express Success" campaign launch event with Allergan and Dress for Success on June 30 in New York City's Union Square. The event includes a celebrity "Rack Relay Race" and clothing drive. The public is invited to join Vanessa in the race by donating nearly new professional clothing and registering to race on ExpressSuccessCampaign.com. The first 100 people to pre-register online and participate in the "Rack Relay Race" will receive a certificate for a physician consultation and, if appropriate, a complimentary BOTOX(R) Cosmetic treatment from a licensed and trained aesthetic-specialty physician. The winning "Rack Relay Race" team also will win an opportunity to have lunch with Vanessa Williams in New York City.
Additional information about the launch and local events is available on the campaign Web site which also features an inspiring animated video featuring Vanessa Williams and three Dress for Success graduates directed by Dex Deboree, a highly acclaimed Grammy(R)-award nominee.
"We are pleased to launch the 'BOTOX(R) Cosmetic: Express Success' campaign on behalf of the women who have helped make BOTOX(R) Cosmetic the most popular physician administered treatment over the past seven years," said Robert Grant, president of Allergan Medical, a division of Allergan, Inc. "During this time, Allergan has developed many programs to educate women about the product, especially the importance of seeing a licensed and trained physician. Through this campaign, Allergan also will be realizing the important philanthropic goal of helping disadvantaged women around the country fulfill their professional potential and express their success. It's a first of its kind campaign for BOTOX(R) Cosmetic and we are proud to be partnering with both Dress for Success and Vanessa Williams on this important mission."
For more information about BOTOX(R) Cosmetic and the "BOTOX(R) Cosmetic: Express Success" campaign, please visit www.ExpressSuccessCampaign.com.
About BOTOX(R) Cosmetic
BOTOX(R) Cosmetic (Botulinum Toxin Type A) was approved by the U.S. Food and Drug Administration (FDA) in 2002 for the temporary improvement in the appearance of moderate to severe glabellar lines (the vertical "frown lines" between the eyebrows) in adult women and men ages 18 to 65. The glabellar lines, which often look like the number "11," can have a negative effect on one's overall facial appearance by creating a sad, angry, or tired impression.
BOTOX(R) Cosmetic has been ranked as the number one physician-administered, aesthetic injectable treatment(2) and 11.8 million treatment sessions with BOTOX(R) Cosmetic have been recorded in the United States alone.(3) High patient satisfaction rates following treatment with BOTOX(R) Cosmetic have been well established with 97 percent of patients indicating satisfaction with the product, according to a survey of approximately 1,000 patients conducted by the research arm of the American Society for Aesthetic Plastic Surgery (ASAPS).(4)
Important BOTOX(R) Cosmetic (Botulinum Toxin Type A) Information
BOTOX(R) Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18 to 65.
For more information about the Botox at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
Important Safety Information
BOTOX(R) Cosmetic injections should not be given to people who have an infection where the physician proposes to inject. They should not be given to people who are known to be sensitive to any ingredient in BOTOX(R) Cosmetic.
Serious heart problems and serious allergic reactions have been reported rarely. If you think you are having an allergic reaction or other reactions, such as difficulty swallowing, speaking, or breathing, call your doctor immediately. The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness, and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious side effects.
The FDA on April 30, 2009, in its update to the early communication sent in 2008, gave the following recommendations:
* Understand that dosage strength (potency) expressed in "Units" or "U" are different among the botulinum toxin products; clinical doses expressed in units are not interchangeable from one botulinum toxin product to another. * Be alert to and educate patients and caregivers about potential adverse events due to distant spread of botulinum toxin effects following local injections including: unexpected loss of strength or muscle weakness, hoarseness or trouble talking (dysphonia), trouble saying words clearly (dysarthria), loss of bladder control, trouble breathing, trouble swallowing, double vision, blurred vision and drooping eyelids. * Understand that these adverse events have been reported as early as several hours and as late as several weeks after treatment. * Advise patients to seek immediate medical attention if they develop any of these symptoms.
About Dress for Success
Dress for Success is an international not-for-profit organization that promotes the economic independence of disadvantaged women by providing professional attire, a network of support and the career development tools to help women thrive in work and in life. Since starting operations in 1997, Dress for Success has expanded to more than 90 cities in the U.S., Canada, Mexico, the Netherlands, New Zealand, Poland, the UK and the West Indies. To date, Dress for Success has helped more than 500,000 women work towards self-sufficiency. Visit http://www.dressforsuccess.org to learn more.
About Vanessa Williams:
Vanessa Williams has achieved success in every area of entertainment, including the worlds of music, theatre, film and television. She has sold millions of albums, earning multiple Grammy(R) Award nominations and countless other awards and honors. She has starred in numerous films, television and Broadway productions and has won or been nominated for the Emmy(R), Golden Globe(R) and Screen Actors Guild(R) awards and has won two NAACP Image Awards for her role as the deliciously wicked Wilhelmina Slater on the hit ABC series, "Ugly Betty." Concord Records will release her 13th album, "The Real Thing" in June and she recently appeared in the box-office hit, "Hannah Montana: The Movie."
About Allergan, Inc.
Founded in 1950, Allergan, Inc., with headquarters in Irvine, California, is a multi-specialty health care company that discovers, develops and commercializes innovative pharmaceuticals, biologics and medical devices that enable people to live life to its greatest potential - to see more clearly, move more freely, express themselves more fully. The Company employs more than 8,000 people worldwide operates state-of-the-art R&D facilities and world-class manufacturing plants. In addition to its discovery-to-development research organization, Allergan has global marketing and sales capabilities with a presence in more than 100 countries.
For more information about the Botox at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
"Dress for Success is about more than providing business attire to women in need. Our mission is to change women's lives by enabling them to express success and confidence in their professional endeavors," said Joi Gordon, CEO of Dress for Success. "We're excited to partner with Allergan and Vanessa Williams to raise awareness of Dress for Success."
As part of the donation to Dress for Success, up to $50,000 of the total $250,000 donation will be generated through an online drive, with Allergan donating $2 to the organization on behalf of each of the first 25,000 people who visit and register on the campaign Web site, ExpressSuccessCampaign.com. When pledging support on the Web site, people also can enter to win a trip for two to New York City to have lunch with Vanessa Williams, read Vanessa's personal blog as well as get interview and workplace tips.
In addition to the donation, the "BOTOX(R) Cosmetic: Express Success" campaign includes a series of educational events featuring campaign ambassador, Vanessa Williams, Dress for Success CEO Joi Gordon and an aesthetic-specialty physician. The events will take place in select markets across the country where consumers will be able to support Dress for Success by donating nearly new professional attire as a cost of entry, while learning about fast and simple tips for working women, including treatment with BOTOX(R) Cosmetic.
"As a working woman and actress, I know how important it is to 'look the part' when interviewing for a new position or in any professional setting. It's no secret that I receive BOTOX(R) Cosmetic treatments, which is a quick procedure that reduces the two frown lines in between my brows that look like an '11' and give me a tired or stressed appearance," said Ms. Williams. "For me, putting my best face forward means finding ways to help other women express their own success, personally and professionally. That's why I'm so excited to be involved with the 'BOTOX(R) Cosmetic: Express Success' campaign benefiting Dress for Success, which has helped more than 500,000 women prepare for, find and keep the job that ultimately leads to financial independence. There is truly no better time to get involved than now, so I ask all women to join our efforts by pledging their support online, joining us at our local events and participating in our New York City launch event."
Vanessa Williams will host the "BOTOX(R) Cosmetic: Express Success" campaign launch event with Allergan and Dress for Success on June 30 in New York City's Union Square. The event includes a celebrity "Rack Relay Race" and clothing drive. The public is invited to join Vanessa in the race by donating nearly new professional clothing and registering to race on ExpressSuccessCampaign.com. The first 100 people to pre-register online and participate in the "Rack Relay Race" will receive a certificate for a physician consultation and, if appropriate, a complimentary BOTOX(R) Cosmetic treatment from a licensed and trained aesthetic-specialty physician. The winning "Rack Relay Race" team also will win an opportunity to have lunch with Vanessa Williams in New York City.
Additional information about the launch and local events is available on the campaign Web site which also features an inspiring animated video featuring Vanessa Williams and three Dress for Success graduates directed by Dex Deboree, a highly acclaimed Grammy(R)-award nominee.
"We are pleased to launch the 'BOTOX(R) Cosmetic: Express Success' campaign on behalf of the women who have helped make BOTOX(R) Cosmetic the most popular physician administered treatment over the past seven years," said Robert Grant, president of Allergan Medical, a division of Allergan, Inc. "During this time, Allergan has developed many programs to educate women about the product, especially the importance of seeing a licensed and trained physician. Through this campaign, Allergan also will be realizing the important philanthropic goal of helping disadvantaged women around the country fulfill their professional potential and express their success. It's a first of its kind campaign for BOTOX(R) Cosmetic and we are proud to be partnering with both Dress for Success and Vanessa Williams on this important mission."
For more information about BOTOX(R) Cosmetic and the "BOTOX(R) Cosmetic: Express Success" campaign, please visit www.ExpressSuccessCampaign.com.
About BOTOX(R) Cosmetic
BOTOX(R) Cosmetic (Botulinum Toxin Type A) was approved by the U.S. Food and Drug Administration (FDA) in 2002 for the temporary improvement in the appearance of moderate to severe glabellar lines (the vertical "frown lines" between the eyebrows) in adult women and men ages 18 to 65. The glabellar lines, which often look like the number "11," can have a negative effect on one's overall facial appearance by creating a sad, angry, or tired impression.
BOTOX(R) Cosmetic has been ranked as the number one physician-administered, aesthetic injectable treatment(2) and 11.8 million treatment sessions with BOTOX(R) Cosmetic have been recorded in the United States alone.(3) High patient satisfaction rates following treatment with BOTOX(R) Cosmetic have been well established with 97 percent of patients indicating satisfaction with the product, according to a survey of approximately 1,000 patients conducted by the research arm of the American Society for Aesthetic Plastic Surgery (ASAPS).(4)
Important BOTOX(R) Cosmetic (Botulinum Toxin Type A) Information
BOTOX(R) Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18 to 65.
For more information about the Botox at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
Important Safety Information
BOTOX(R) Cosmetic injections should not be given to people who have an infection where the physician proposes to inject. They should not be given to people who are known to be sensitive to any ingredient in BOTOX(R) Cosmetic.
Serious heart problems and serious allergic reactions have been reported rarely. If you think you are having an allergic reaction or other reactions, such as difficulty swallowing, speaking, or breathing, call your doctor immediately. The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness, and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious side effects.
The FDA on April 30, 2009, in its update to the early communication sent in 2008, gave the following recommendations:
* Understand that dosage strength (potency) expressed in "Units" or "U" are different among the botulinum toxin products; clinical doses expressed in units are not interchangeable from one botulinum toxin product to another. * Be alert to and educate patients and caregivers about potential adverse events due to distant spread of botulinum toxin effects following local injections including: unexpected loss of strength or muscle weakness, hoarseness or trouble talking (dysphonia), trouble saying words clearly (dysarthria), loss of bladder control, trouble breathing, trouble swallowing, double vision, blurred vision and drooping eyelids. * Understand that these adverse events have been reported as early as several hours and as late as several weeks after treatment. * Advise patients to seek immediate medical attention if they develop any of these symptoms.
About Dress for Success
Dress for Success is an international not-for-profit organization that promotes the economic independence of disadvantaged women by providing professional attire, a network of support and the career development tools to help women thrive in work and in life. Since starting operations in 1997, Dress for Success has expanded to more than 90 cities in the U.S., Canada, Mexico, the Netherlands, New Zealand, Poland, the UK and the West Indies. To date, Dress for Success has helped more than 500,000 women work towards self-sufficiency. Visit http://www.dressforsuccess.org to learn more.
About Vanessa Williams:
Vanessa Williams has achieved success in every area of entertainment, including the worlds of music, theatre, film and television. She has sold millions of albums, earning multiple Grammy(R) Award nominations and countless other awards and honors. She has starred in numerous films, television and Broadway productions and has won or been nominated for the Emmy(R), Golden Globe(R) and Screen Actors Guild(R) awards and has won two NAACP Image Awards for her role as the deliciously wicked Wilhelmina Slater on the hit ABC series, "Ugly Betty." Concord Records will release her 13th album, "The Real Thing" in June and she recently appeared in the box-office hit, "Hannah Montana: The Movie."
About Allergan, Inc.
Founded in 1950, Allergan, Inc., with headquarters in Irvine, California, is a multi-specialty health care company that discovers, develops and commercializes innovative pharmaceuticals, biologics and medical devices that enable people to live life to its greatest potential - to see more clearly, move more freely, express themselves more fully. The Company employs more than 8,000 people worldwide operates state-of-the-art R&D facilities and world-class manufacturing plants. In addition to its discovery-to-development research organization, Allergan has global marketing and sales capabilities with a presence in more than 100 countries.
FDA On Wrinkle Relief: Injectable Cosmetic Fillers
In the quest for youth—or at least a more youthful appearance—women and men are seeking treatments to minimize laugh lines, crow's feet, and forehead furrows. A popular treatment involves injecting cosmetic wrinkle fillers into the face.
For more information about the Facial Fillers at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=176
Injectable cosmetic wrinkle fillers are soft tissue fillers approved as medical devices by the Food and Drug Administration (FDA). These devices are injected into the skin to help fill in facial wrinkles, restoring a smoother appearance. Most of these wrinkle fillers are temporary because they are eventually absorbed by the body.
Some people may need more than one injection to achieve the wrinkle-smoothing effect. The effect lasts for about six months or longer.
Successful results depend on
health of the skin
skill of the doctor
type of filler used
Uses
FDA has approved absorbable injectable cosmetic wrinkle fillers for correcting soft tissue contour defects, such as moderate and severe wrinkles and folds. Some absorbable fillers are approved for restoring or correcting the signs of facial fat loss in people with human immunodeficiency virus (HIV).
The only non-absorbable FDA-approved injectable cosmetic wrinkle filler is for correcting facial tissue around the mouth.
FDA-approved cosmetic wrinkle fillers should not be used for
plumping the lips (lip augmentation)
increasing breast size (breast augmentation)
implanting into bone, tendon, ligament, or muscle
implanting into blood vessels
Filler Materials
Wrinkle fillers are made of various types of materials, and some include a combination of products. Some products also contain lidocaine, which numbs the skin at the injection site.
The materials used in injectable cosmetic wrinkle fillers include
Temporary (absorbable) fillers
Collagen injections are made of highly purified cow or human collagen. Collagen is a natural protein that is a major component of skin and other tissues in the body.
Hyaluronic acid gel is a protective lubricating gel, produced naturally by the body, that binds with water to plump the skin.
Calcium hydroxylapatite is a mineral that is a major component of bone. Calcium hydroxylapatite is a well-matched (biocompatible) material that dissolves in the body (biodegradable) and is implanted in the form of a gel.
Poly-L-lactic acid (PLLA) is a biodegradable, biocompatible, synthetic material from the alpha-hydroxy-acid family that has been widely used for many years in dissolvable stitches and bone screws.
Permanent (non-absorbable) filler
Polymethylmethacrylate beads (PMMA microspheres) are tiny round, smooth plastic particles that have been tested to be biocompatible. They are not absorbed by the body.
Risks
Getting injected with cosmetic wrinkle fillers is an elective procedure. As with any medical procedure, it poses risks.
Possible side effects include
infection
Bruising
redness
swelling
pain
tenderness
itching and rash
raised bumps of skin (nodules or granulomas) that may need to be surgically removed
death of skin, which may cause disfiguration, if the cosmetic wrinkle filler is injected and blocks a blood vessel
sore (abscess) at the injection site
wrinkle filler that breaks through the skin
open or draining wounds
blurred vision and flu-like symptoms
increased allergic reaction that may lead to a severe allergic reaction (anaphylactic shock) that requires emergency medical help. (Your doctor may request a pre-treatment allergy test to determine if you are allergic to the filler.)
Most side effects occur shortly after injection and go away within seven days. In some cases, side effects may emerge weeks, months, or years later. A non-absorbable filler may cause long-term side effects.
You should not use cosmetic wrinkle fillers if any of the following applies to you:
severe allergies marked by a history of anaphylactic shock
allergy to cow collagen or eggs
allergy to lidocaine
inflamed or infected skin
prone to form excessive scarring (keloid) or thick scarring (hypertrophic scars)
bleeding disorder
active inflammatory condition (cysts, pimples, rashes or hives) or infection; you should postpone treatment until the condition is controlled.
Tips for Consumers
Before deciding to get injected with a cosmetic wrinkle filler:
Be aware that the safety of these products is unknown for use in pregnant or breastfeeding women or in patients under 18 years of age.
Be aware that the safety is unknown when these products are used with Botox or other wrinkle therapies.
Be aware that the safety of these fillers has only been studied when used in the face.
Know the type of product that will be injected and all of its possible side effects.
Discuss fillers with a doctor who can refer you to a specialist in the fields of dermatology and aesthetic plastic surgery.
Select a doctor who is trained to do the procedure. (You may want to contact the American Academy of Dermatology at www.aad.org or the American Society for Aesthetic Plastic Surgery at www.surgery.org.)
Have realistic expectations about the benefits you want to achieve and discuss them with your doctor.
For more information about the Facial Fillers at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=176
This article appears on FDA's Consumer Health Information Web page (www.fda.gov/consumer), which features the latest on all FDA-regulated products. Sign up for free e-mail subscriptions at www.fda.gov/consumer/consumerenews.html.
What About Botox?
Botox Cosmetic is an injectable drug, but it is not a wrinkle filler. Instead of filling the wrinkle, it keeps muscles from tightening so the wrinkles don’t show as much. FDA has approved Botox Cosmetic only to treat wrinkles between the eyebrows.
For more information about the Facial Fillers at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=176
Injectable cosmetic wrinkle fillers are soft tissue fillers approved as medical devices by the Food and Drug Administration (FDA). These devices are injected into the skin to help fill in facial wrinkles, restoring a smoother appearance. Most of these wrinkle fillers are temporary because they are eventually absorbed by the body.
Some people may need more than one injection to achieve the wrinkle-smoothing effect. The effect lasts for about six months or longer.
Successful results depend on
health of the skin
skill of the doctor
type of filler used
Uses
FDA has approved absorbable injectable cosmetic wrinkle fillers for correcting soft tissue contour defects, such as moderate and severe wrinkles and folds. Some absorbable fillers are approved for restoring or correcting the signs of facial fat loss in people with human immunodeficiency virus (HIV).
The only non-absorbable FDA-approved injectable cosmetic wrinkle filler is for correcting facial tissue around the mouth.
FDA-approved cosmetic wrinkle fillers should not be used for
plumping the lips (lip augmentation)
increasing breast size (breast augmentation)
implanting into bone, tendon, ligament, or muscle
implanting into blood vessels
Filler Materials
Wrinkle fillers are made of various types of materials, and some include a combination of products. Some products also contain lidocaine, which numbs the skin at the injection site.
The materials used in injectable cosmetic wrinkle fillers include
Temporary (absorbable) fillers
Collagen injections are made of highly purified cow or human collagen. Collagen is a natural protein that is a major component of skin and other tissues in the body.
Hyaluronic acid gel is a protective lubricating gel, produced naturally by the body, that binds with water to plump the skin.
Calcium hydroxylapatite is a mineral that is a major component of bone. Calcium hydroxylapatite is a well-matched (biocompatible) material that dissolves in the body (biodegradable) and is implanted in the form of a gel.
Poly-L-lactic acid (PLLA) is a biodegradable, biocompatible, synthetic material from the alpha-hydroxy-acid family that has been widely used for many years in dissolvable stitches and bone screws.
Permanent (non-absorbable) filler
Polymethylmethacrylate beads (PMMA microspheres) are tiny round, smooth plastic particles that have been tested to be biocompatible. They are not absorbed by the body.
Risks
Getting injected with cosmetic wrinkle fillers is an elective procedure. As with any medical procedure, it poses risks.
Possible side effects include
infection
Bruising
redness
swelling
pain
tenderness
itching and rash
raised bumps of skin (nodules or granulomas) that may need to be surgically removed
death of skin, which may cause disfiguration, if the cosmetic wrinkle filler is injected and blocks a blood vessel
sore (abscess) at the injection site
wrinkle filler that breaks through the skin
open or draining wounds
blurred vision and flu-like symptoms
increased allergic reaction that may lead to a severe allergic reaction (anaphylactic shock) that requires emergency medical help. (Your doctor may request a pre-treatment allergy test to determine if you are allergic to the filler.)
Most side effects occur shortly after injection and go away within seven days. In some cases, side effects may emerge weeks, months, or years later. A non-absorbable filler may cause long-term side effects.
You should not use cosmetic wrinkle fillers if any of the following applies to you:
severe allergies marked by a history of anaphylactic shock
allergy to cow collagen or eggs
allergy to lidocaine
inflamed or infected skin
prone to form excessive scarring (keloid) or thick scarring (hypertrophic scars)
bleeding disorder
active inflammatory condition (cysts, pimples, rashes or hives) or infection; you should postpone treatment until the condition is controlled.
Tips for Consumers
Before deciding to get injected with a cosmetic wrinkle filler:
Be aware that the safety of these products is unknown for use in pregnant or breastfeeding women or in patients under 18 years of age.
Be aware that the safety is unknown when these products are used with Botox or other wrinkle therapies.
Be aware that the safety of these fillers has only been studied when used in the face.
Know the type of product that will be injected and all of its possible side effects.
Discuss fillers with a doctor who can refer you to a specialist in the fields of dermatology and aesthetic plastic surgery.
Select a doctor who is trained to do the procedure. (You may want to contact the American Academy of Dermatology at www.aad.org or the American Society for Aesthetic Plastic Surgery at www.surgery.org.)
Have realistic expectations about the benefits you want to achieve and discuss them with your doctor.
For more information about the Facial Fillers at Derma Health Institute.com, go to:
http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=176
This article appears on FDA's Consumer Health Information Web page (www.fda.gov/consumer), which features the latest on all FDA-regulated products. Sign up for free e-mail subscriptions at www.fda.gov/consumer/consumerenews.html.
What About Botox?
Botox Cosmetic is an injectable drug, but it is not a wrinkle filler. Instead of filling the wrinkle, it keeps muscles from tightening so the wrinkles don’t show as much. FDA has approved Botox Cosmetic only to treat wrinkles between the eyebrows.
Wednesday, April 29, 2009
Allergan, Inc. Marks 20 Years Since Botox First Approved By FDA
IRVINE, Calif., April 15, 2009 — It has been nearly 20 years since BOTOX® was first approved by the FDA to treat two specific eye muscle disorders. Since 1989, the FDA has approved two additional therapeutic indications for BOTOX® and one aesthetic indication, using the same formulation and under the name BOTOX® Cosmetic (Botulinum Toxin Type A), with dosing specific to temporarily treat moderate to severe glabellar lines in people ages 18 to 65. To date, BOTOX® is approved for 20 different therapeutic indications in approximately 80 countries worldwide. BOTOX® Cosmetic is authorized for aesthetic treatment in approximately 60 countries.
For more information about Botox at Derma Health Institute, go to:http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
The Webinar also featured a new video demonstrating in detail how BOTOX® therapy works by blocking overactive nerve impulses that trigger excessive muscle contractions or glandular activity.
"One of the advantages of BOTOX® therapy is its highly selective mechanism of action and targeted mode of administration, via injection directly into the affected muscle or gland, which in large part explains the product's clinical performance and predictable patient outcomes," explained Mitchell F. Brin, M.D., Allergan's Senior Vice President of Global Development and Chief Scientific Officer for BOTOX®.
No Two Botulinum Toxins Are AlikeWith additional botulinum toxin products awaiting FDA approval, Dr. Brin reviewed the scientific differences among botulinum toxin therapies and the factors that physicians and patients should weigh when considering treatment options.
"The well-established risk/benefit profile of BOTOX® is unique to the product, because no two botulinum toxins are alike," said Dr. Brin. He pointed out that botulinum toxin products are biologics – i.e., derived from living substances, in this case, from the Clostridium botulinum bacteria. This bacteria produces seven different subtypes of botulinum toxin, with type A being the most potent. Differences among subtypes may influence therapeutic effects and how long they last, or the occurrence of adverse events following treatment. Even among botulinum toxin products of the same subtype, variations in manufacturing processes can result in differences in the product's characteristics, including formulation (e.g., molecular uniformity and weights of toxin complexes), pharmacokinetics, and clinical parameters such as efficacy, duration of effect, risk/benefit profile and immunogenicity.
"Because of these differences, each botulinum toxin also has distinct dosing requirements," said Dr. Brin. "Importantly for physicians and patients, this means that BOTOX® is not interchangeable with other botulinum toxins and a physician cannot simply use a fixed-dose ratio and expect the same precise and predictable results."
The Patient and Physician ExperienceWhile practicing in the 1980s at Columbia-Presbyterian Medical Center in New York City, Dr. Brin, a neurologist, co-led one of the first clinical trials of BOTOX® (Botulinum Toxin Type A) as a treatment for cervical dystonia supported by the Food and Drug Administration's Office of Orphan Product Development, when a young man named Tom Stampe was referred to him.
"I was 23 years old, and I started getting this very bad neck pain," said Mr. Stampe. "One day the neck pain started making me go into a twitch and my head started pulling to one side to the point that it stayed stuck on my right shoulder. For three years I couldn't move it, couldn't turn it, couldn't do anything. After years of misdiagnosis and disability, I was finally referred to Dr. Brin who diagnosed my condition as cervical dystonia. At that time they were trying out a new investigational drug, and he thought I'd be a very good candidate for it. It was BOTOX®. Shortly after those first injections my head and neck began to move freely, and it's a feeling I'll never forget." Today, Mr. Stampe is an advocate for cervical dystonia patients and currently serves as President of the New York chapter of the Dystonia Medical Research Foundation.
"The clinical development of BOTOX® (Botulinum Toxin Type A) has improved the management of a number of disabling conditions characterized by excessive muscle or glandular activity, and just as importantly for patients like Mr. Stampe, it has expanded interest in their diagnosis and treatment," said Joseph Jankovic, M.D., Professor of Neurology, Distinguished Chair in Movement Disorders, and Director of the Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine in Houston, Texas. Dr. Jankovic, a leader in the field of neurotoxin research, led the first studies of BOTOX® for the treatment of cervical dystonia and blepharospasm in the 1980s.
"Now it is decades later, and we have a wealth of clinical data on BOTOX®, as well as expertise in its administration and a thorough scientific understanding of the product, and we know that optimal results with BOTOX® depend on several critical factors," explained Dr. Jankovic. "Unlike oral drugs, there are many technical aspects involved in administering BOTOX®, including dosing, dilution and injection placement and technique. Therefore, the injecting physician should have extensive knowledge of these treatment factors, along with a thorough understanding of the disease and its symptoms to ensure the product can deliver a targeted and precise effect." Dr. Jankovic emphasized the importance to patients, whether they are considering medical treatment with BOTOX® or aesthetic treatment with BOTOX® Cosmetic (Botulinum Toxin Type A), of seeking a well-trained physician with the qualifications necessary to evaluate and determine the best injection plan for each patient.
BOTOX® Research and DevelopmentIn concluding the Webinar, Scott Whitcup, M.D., Allergan's Executive Vice President for Research and Development, noted that Allergan is building upon its two decades of research and clinical experience with BOTOX® to investigate new medical uses for the product, with research focused on areas where safe and effective new treatment options will make a meaningful difference to large numbers of patients. Allergan also is exploring novel next generation neurotoxins with the potential for even more specific modes of action.
About BOTOX®BOTOX® was first approved by the FDA in 1989 for the blepharospasm (excessive eye blinking) and strabismus (misalignment of the eye). Since then BOTOX® also has been approved by the FDA for the treatment of cervical dystonia (a painful twisting of the neck) and severe primary axillary hyperhidrosis (excessive underarm sweating that is inadequately managed by topical agents). The same product, with dosing specific to treat glabellar lines (vertical frown lines between the brows), received FDA approval in 2002 under the name BOTOX® Cosmetic (to differentiate between its therapeutic and aesthetic applications). With that approval, BOTOX® Cosmetic has been the most popular physician-administered, aesthetic injectable treatment for the past seven years.2
Nearly 17 million treatment sessions with BOTOX® and BOTOX® Cosmetic have been recorded in the United States alone over the past 14 years,3 with approximately 22 million vials of BOTOX® and BOTOX® Cosmetic distributed worldwide to date.4 In addition to this extensive clinical experience with the product, the safety and efficacy of BOTOX® has been studied in approximately 50 randomized, placebo-controlled clinical trials.5 Additionally, approximately 11,000 patients have been treated with BOTOX® and BOTOX® Cosmetic in Allergan-sponsored trials.6 With approximately 2,000 articles on BOTOX® and BOTOX® Cosmetic in peer-reviewed publications, BOTOX® is the most widely researched neurotoxin, and one of the most widely researched medicines in the world.
Important BOTOX® (Botulinum Toxin Type A) and BOTOX® Cosmetic (Botulinum Toxin Type A) InformationBOTOX® is approved for the treatment of cervical dystonia in adults to decrease the severity of abnormal head position and neck pain associated with cervical dystonia.
BOTOX® is approved for the treatment of strabismus and blepharospasm associated with dystonia, including benign essential blepharospasm or VII nerve disorders in patients 12 years of age and above.
The efficacy of BOTOX® treatment in deviations over 50 prism diopters, in restrictive strabismus, in Duane's syndrome with lateral rectus weakness, and in secondary strabismus caused by prior surgical over-recession of the antagonist has not been established. BOTOX® is ineffective in chronic paralytic strabismus except when used in conjunction with surgical repair to reduce antagonist contracture.
And BOTOX® is approved for the treatment of severe primary axillary hyperhidrosis that is inadequately managed with topical agents.
For more information about Botox at Derma Health Institute, go to:http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
BOTOX® Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18 – 65.
About Allergan, Inc.Founded in 1950, Allergan, Inc., with headquarters in Irvine, California, is a multi-specialty health care company that discovers, develops and commercializes innovative pharmaceuticals, biologics and medical devices that enable people to live life to its greatest potential – to see more clearly, move more freely, express themselves more fully. The Company employs approximately 8,500 people worldwide and operates state-of-the-art R&D facilities and world-class manufacturing plants. In addition to its discovery-to-development research organization, Allergan has global marketing and sales capabilities with a presence in more than 100 countries.
For more information about Botox at Derma Health Institute, go to:http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
The Webinar also featured a new video demonstrating in detail how BOTOX® therapy works by blocking overactive nerve impulses that trigger excessive muscle contractions or glandular activity.
"One of the advantages of BOTOX® therapy is its highly selective mechanism of action and targeted mode of administration, via injection directly into the affected muscle or gland, which in large part explains the product's clinical performance and predictable patient outcomes," explained Mitchell F. Brin, M.D., Allergan's Senior Vice President of Global Development and Chief Scientific Officer for BOTOX®.
No Two Botulinum Toxins Are AlikeWith additional botulinum toxin products awaiting FDA approval, Dr. Brin reviewed the scientific differences among botulinum toxin therapies and the factors that physicians and patients should weigh when considering treatment options.
"The well-established risk/benefit profile of BOTOX® is unique to the product, because no two botulinum toxins are alike," said Dr. Brin. He pointed out that botulinum toxin products are biologics – i.e., derived from living substances, in this case, from the Clostridium botulinum bacteria. This bacteria produces seven different subtypes of botulinum toxin, with type A being the most potent. Differences among subtypes may influence therapeutic effects and how long they last, or the occurrence of adverse events following treatment. Even among botulinum toxin products of the same subtype, variations in manufacturing processes can result in differences in the product's characteristics, including formulation (e.g., molecular uniformity and weights of toxin complexes), pharmacokinetics, and clinical parameters such as efficacy, duration of effect, risk/benefit profile and immunogenicity.
"Because of these differences, each botulinum toxin also has distinct dosing requirements," said Dr. Brin. "Importantly for physicians and patients, this means that BOTOX® is not interchangeable with other botulinum toxins and a physician cannot simply use a fixed-dose ratio and expect the same precise and predictable results."
The Patient and Physician ExperienceWhile practicing in the 1980s at Columbia-Presbyterian Medical Center in New York City, Dr. Brin, a neurologist, co-led one of the first clinical trials of BOTOX® (Botulinum Toxin Type A) as a treatment for cervical dystonia supported by the Food and Drug Administration's Office of Orphan Product Development, when a young man named Tom Stampe was referred to him.
"I was 23 years old, and I started getting this very bad neck pain," said Mr. Stampe. "One day the neck pain started making me go into a twitch and my head started pulling to one side to the point that it stayed stuck on my right shoulder. For three years I couldn't move it, couldn't turn it, couldn't do anything. After years of misdiagnosis and disability, I was finally referred to Dr. Brin who diagnosed my condition as cervical dystonia. At that time they were trying out a new investigational drug, and he thought I'd be a very good candidate for it. It was BOTOX®. Shortly after those first injections my head and neck began to move freely, and it's a feeling I'll never forget." Today, Mr. Stampe is an advocate for cervical dystonia patients and currently serves as President of the New York chapter of the Dystonia Medical Research Foundation.
"The clinical development of BOTOX® (Botulinum Toxin Type A) has improved the management of a number of disabling conditions characterized by excessive muscle or glandular activity, and just as importantly for patients like Mr. Stampe, it has expanded interest in their diagnosis and treatment," said Joseph Jankovic, M.D., Professor of Neurology, Distinguished Chair in Movement Disorders, and Director of the Parkinson's Disease Center and Movement Disorders Clinic, Baylor College of Medicine in Houston, Texas. Dr. Jankovic, a leader in the field of neurotoxin research, led the first studies of BOTOX® for the treatment of cervical dystonia and blepharospasm in the 1980s.
"Now it is decades later, and we have a wealth of clinical data on BOTOX®, as well as expertise in its administration and a thorough scientific understanding of the product, and we know that optimal results with BOTOX® depend on several critical factors," explained Dr. Jankovic. "Unlike oral drugs, there are many technical aspects involved in administering BOTOX®, including dosing, dilution and injection placement and technique. Therefore, the injecting physician should have extensive knowledge of these treatment factors, along with a thorough understanding of the disease and its symptoms to ensure the product can deliver a targeted and precise effect." Dr. Jankovic emphasized the importance to patients, whether they are considering medical treatment with BOTOX® or aesthetic treatment with BOTOX® Cosmetic (Botulinum Toxin Type A), of seeking a well-trained physician with the qualifications necessary to evaluate and determine the best injection plan for each patient.
BOTOX® Research and DevelopmentIn concluding the Webinar, Scott Whitcup, M.D., Allergan's Executive Vice President for Research and Development, noted that Allergan is building upon its two decades of research and clinical experience with BOTOX® to investigate new medical uses for the product, with research focused on areas where safe and effective new treatment options will make a meaningful difference to large numbers of patients. Allergan also is exploring novel next generation neurotoxins with the potential for even more specific modes of action.
About BOTOX®BOTOX® was first approved by the FDA in 1989 for the blepharospasm (excessive eye blinking) and strabismus (misalignment of the eye). Since then BOTOX® also has been approved by the FDA for the treatment of cervical dystonia (a painful twisting of the neck) and severe primary axillary hyperhidrosis (excessive underarm sweating that is inadequately managed by topical agents). The same product, with dosing specific to treat glabellar lines (vertical frown lines between the brows), received FDA approval in 2002 under the name BOTOX® Cosmetic (to differentiate between its therapeutic and aesthetic applications). With that approval, BOTOX® Cosmetic has been the most popular physician-administered, aesthetic injectable treatment for the past seven years.2
Nearly 17 million treatment sessions with BOTOX® and BOTOX® Cosmetic have been recorded in the United States alone over the past 14 years,3 with approximately 22 million vials of BOTOX® and BOTOX® Cosmetic distributed worldwide to date.4 In addition to this extensive clinical experience with the product, the safety and efficacy of BOTOX® has been studied in approximately 50 randomized, placebo-controlled clinical trials.5 Additionally, approximately 11,000 patients have been treated with BOTOX® and BOTOX® Cosmetic in Allergan-sponsored trials.6 With approximately 2,000 articles on BOTOX® and BOTOX® Cosmetic in peer-reviewed publications, BOTOX® is the most widely researched neurotoxin, and one of the most widely researched medicines in the world.
Important BOTOX® (Botulinum Toxin Type A) and BOTOX® Cosmetic (Botulinum Toxin Type A) InformationBOTOX® is approved for the treatment of cervical dystonia in adults to decrease the severity of abnormal head position and neck pain associated with cervical dystonia.
BOTOX® is approved for the treatment of strabismus and blepharospasm associated with dystonia, including benign essential blepharospasm or VII nerve disorders in patients 12 years of age and above.
The efficacy of BOTOX® treatment in deviations over 50 prism diopters, in restrictive strabismus, in Duane's syndrome with lateral rectus weakness, and in secondary strabismus caused by prior surgical over-recession of the antagonist has not been established. BOTOX® is ineffective in chronic paralytic strabismus except when used in conjunction with surgical repair to reduce antagonist contracture.
And BOTOX® is approved for the treatment of severe primary axillary hyperhidrosis that is inadequately managed with topical agents.
For more information about Botox at Derma Health Institute, go to:http://www.dermahealthinstitute.com/catalog/product_info.php?products_id=175
BOTOX® Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18 – 65.
About Allergan, Inc.Founded in 1950, Allergan, Inc., with headquarters in Irvine, California, is a multi-specialty health care company that discovers, develops and commercializes innovative pharmaceuticals, biologics and medical devices that enable people to live life to its greatest potential – to see more clearly, move more freely, express themselves more fully. The Company employs approximately 8,500 people worldwide and operates state-of-the-art R&D facilities and world-class manufacturing plants. In addition to its discovery-to-development research organization, Allergan has global marketing and sales capabilities with a presence in more than 100 countries.
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