Showing posts with label Vitamins. Show all posts
Showing posts with label Vitamins. Show all posts

Wednesday, July 28, 2010

Report: Vitamins for the Treatment of Sun-Damaged Skin

SCHAUMBURG, Ill., April 12 -- While everyone knows that getting an adequate daily dose of vitamins and minerals is important in maintaining one's overall health, many question whether or not the vitamins touted in skin care products work in reducing the signs of sun-damaged skin. Now, a new study reviews the currently published scientific literature to determine what evidence exists to support the use of vitamins in skin care products to slow or reverse the effects of sun damage.

In the report entitled, "Vitamins and photoaging: Do scientific data support their use?", published online in the Journal of the American Academy of Dermatology, dermatologist Jenny Kim, M.D., Ph.D., FAAD, associate professor in the division of dermatology, department of medicine, at the University of California, Los Angeles (UCLA), David Geffen School of Medicine in Los Angeles, presented results of a study that may support the use of certain vitamins in oral or topical formulations.

"It is well documented that ultraviolet (UV) radiation contributes to premature skin aging through the process of photoaging, and there is increasing evidence that the antioxidant properties of vitamins may contribute to the prevention and treatment of photoaging," said Dr. Kim. "In fact, numerous companies developing cosmeceuticals base their effectiveness claims on the fact that their formulations contain vitamins proven in laboratories to modify cellular processes thought to contribute to the appearance of photoaged skin. As dermatologists, we can help our patients navigate this maze of marketing claims by sharing scientific data on the known efficacy of vitamins in skin care products."

Based on a comprehensive review of the available published data on the role of vitamins in skin care products, Dr. Kim and her colleagues, Jamie Zussman, M.D., FAAD, and Jennifer Ahdout, M.D., found there is evidence to support the potential role of vitamins A, C, E, and B3 in modifying the photoaging process.

"While it's evident that these vitamins can play a role in fighting sun damage, the question still remains whether these properties are effective when delivered in skin care products," notes Dr Kim.

Vitamin A: Effective in treating a variety of skin conditions

The two most common forms of vitamin A studied for their role in protecting the skin from UV-induced damage are retinols and carotenoids. Retinol is found in foods such as liver, milk and eggs, and is the most biologically active form of the vitamin. Carotenoids are found in many fruits and vegetables, and have strong antioxidant capabilities.

While carotenoids are not shown to be beneficial in the treatment of photoaging, research suggests that they may play a role in photoprotection by preventing UV-induced collagen breakdown.

"Although the evidence available at this time is not strong enough to offer definitive support for the use of dietary carotenoids for photoprotection, a role for carotenoids as a supplement to photoprotective agents should not be discounted yet," said Dr. Kim. "We hope to see larger-scale clinical trials conducted to further explore the photoprotective effects of carotenoids."

Unlike carotenoids, there is vast evidence supporting the role of topical retinoids (the class of substances formed by retinol and its natural and synthetic derivatives) in treating photoaged skin. For example, prescription retinoid formulations have the most scientific data to support their use in this area.

Dr. Kim noted that both tretinoin cream (0.025% and 0.05%) and tazarotene cream (0.1%) are already FDA-approved for the treatment of fine wrinkles, skin roughness and mottled hyperpigmentation caused by aging and sun exposure. In addition, she added that studies of other retinoids have shown that a once-daily application of 0.1% isotretinoin cream for 36 weeks was effective in reducing fine wrinkles.

Retinoids also are found in over-the-counter cosmeceuticals, but there is less clinical evidence supporting their effectiveness in improving photoaged skin. "An important point to remember with retinoids is that we cannot assume that all retinoids are equal in their ability to fight photoaging," said Dr. Kim. "In over-the-counter products, retinol appears to be the most effective retinoid based on clinical studies completed to date. However, patients should consult their dermatologist before using any topical retinoid, as side effects can occur when used with other topical products. When properly instructed by a dermatologist, most patients can tolerate topical retinoids and benefit from their effect."

Dr. Kim added that unlike topical retinoids, there is minimal evidence supporting the use of oral retinoids in the treatment of photoaging.

Vitamin C: Possible skin care product value

Vitamin C, a water-soluble vitamin also known as ascorbic acid that is found in citrus fruits and dark green leafy vegetables, plays an essential role in the production of collagen and elastin. Because of its antioxidant properties, vitamin C may reverse the negative effects of UV radiation in the skin, but there are few clinically controlled studies to confirm this theory.

"An animal study examining the role of vitamin C in reversing sun damage found that when 5% ascorbate was applied two hours before UVB and UVA exposure, UVB-induced skin wrinkling was reduced," said Dr. Kim. "Some of the human clinical trials have shown similar favorable results when applying a daily dose of L-ascorbic acid treatment, but all of these studies involved small sample sizes."

In addition, Dr. Kim pointed out that one concern of adding vitamin C to cosmeceuticals is that vitamin C is unstable when used in formulations, and it is not known how much, if any, intact molecule remains when applied to the skin.

"This problem has been partially overcome by chemically modifying ascorbic acid," said Dr. Kim. "However, for the body to use the supplied ascorbic acid, it must convert it to L-ascorbic acid, and many of the stabilized, commercially available forms have not been examined to determine whether this conversion is possible. For that reason, the average consumer will not be able to determine if a cosmeceutical containing vitamin C will be effective."

Vitamin E: A primary antioxidant

Vitamin E, or tocopherol, is a fat-soluble vitamin, and its synthetic form is found in many over-the-counter products. Working as an antioxidant, vitamin E protects cell membranes and is thought to play an important role in skin aging because of its antioxidant properties. While topical vitamin E is available in a variety of products, there is no data which support claims that it improves skin wrinkling, discoloration and texture.

"Topical vitamin E has been studied in humans, as in mice, more as a protectant to be used before sun exposure than as an agent to be included in cosmeceuticals to reduce the signs of skin aging," said Dr. Kim. "Through research we have learned that UV exposure significantly decreases levels of cutaneous vitamin E, and vitamin C should be included in any formulation containing vitamin E because of the important role it plays in maintaining active vitamin E levels."

Research also has explored combining vitamins E and C as an oral supplement to provide sun protection. Multiple studies suggest that this combination therapy is beneficial for photoprotection. However, Dr. Kim noted that overzealous oral vitamin E supplements may be harmful, and two new studies also suggest that a high intake of vitamin E may be associated with an increased risk of basal cell carcinoma.

Vitamin B3: A possible treatment for photoaging

The B vitamins consist of eight different water-soluble vitamins that are found in a variety of foods. Vitamin B3 has been shown to reduce blood cholesterol and atherosclerosis (a condition in which fatty materials collect along artery walls), but now new insights are examining its role as an effective treatment for several skin conditions – from acne to photoaging.

Specifically, Dr. Kim noted that vitamin B3 has been found to increase collagen production in in vitro studies and to reduce skin hyperpigmentation (dark spots) in clinical studies.

"There has been one clinical trial conducted in Caucasian women in which 50 women applied 5% niacinamide (topical vitamin B3) to one side of their faces twice per day for 12 weeks, and these women experienced significant reductions in the appearance of hyperpigmented spots, redness, wrinkles, and yellowing, as well as improved skin elasticity," said Dr. Kim. "While initial studies show promise that topical vitamin B3 may prevent UV-induced skin aging, larger clinical trials are needed to confirm its role as a definitive treatment of photoaging."

Bottom Line: Maintain healthy lifestyle, healthy diet, practice sun protection

Dr. Kim added that it is important for everyone to get an adequate daily supply of vitamins to maintain a healthy lifestyle, and any insufficiencies may negatively impact the skin's overall appearance.

"Research has shown a potential role for various vitamins in reducing the damaging effects of sun exposure on the skin. Whether topical or oral formulations containing these vitamins have a protective effect is uncertain. Given the number, type and variability of preparations available, consumers should understand from our study that skin care products with vitamins may not provide clinically meaningful improvement," said Dr. Kim. "What is known is that proper sun protection is key to the prevention of photoaging and should be top of mind at all times."

For more information on improving the appearance of your skin, go to the "AgingSkinNet" section of www.SkinCarePhysicians.com, a Web site developed by dermatologists that provides patients with up-to-date information on the treatment and management of disorders of the skin, hair and nails.

Headquartered in Schaumburg, Ill., the American Academy of Dermatology (Academy), founded in 1938, is the largest, most influential, and most representative of all dermatologic associations. With a membership of more than 16,000 physicians worldwide, the Academy is committed to: advancing the diagnosis and medical, surgical and cosmetic treatment of the skin, hair and nails; advocating high standards in clinical practice, education, and research in dermatology; and supporting and enhancing patient care for a lifetime of healthier skin, hair and nails. For more information, contact the Academy at 1-888-462-DERM (3376) or www.aad.org.

Thursday, October 15, 2009

Anti Aging and Skin Care: Why Does the Skin Wrinkle?

The aging process begins when we enter the world and the effects of aging are evident in our bodies through our lives. From the 20’s, the signs of aging start to become noticeable. Genetically programmed chronologic aging causes changes in collagen and elastin, the connective tissues that firmness and elasticity of supply to the skin. The genetic program of individuals is different, so the loss of firmness and skin elasticity occurs at different rates and different times in one individual, compared to another. As the skin becomes less elastic, fat also becomes drier and underlying begins to disappear. With the loss of underlying support by fat padding and connective tissue, skin begins to sag, it appears less supple and wrinkles form.

Although wrinkles, lines and age spots are formed by the natural effect of aging, a way to avoid appearing early in life is to avoid direct sunlight and use sunscreens with a SPF 15 or higher. And while most of us have some form of sun-damaged skin, there are ways to regain healthy, smooth skin. After many years of research, scientists, dermatologists and plastic surgeons have discovered that a variety of natural ingredients and vitamin extracts significantly help slow and even reverse the signs of skin aging. These ingredients are now found in many developed countries, the doctor and the doctor recommends care products anti-aging skin, as detailed below.

Vitamin A (Retinol) – Topical Vitamin A has been suggested to help build collagen fibers in the skin, in addition to its more superficial exfoliating properties. This is the basis for use in minimizing the appearance of fine wrinkles. Vitamin A or Retinol is the main ingredient in TYK young again, MD Forte, DDF and products SkinScience.

Vitamin C – Vitamin C or ascorbic acid acts as an antioxidant and is considered vital in wound healing because it aids in stabilizing collagen. When applied topically, vitamin C can reduce fine lines and wrinkles, and may decrease the severity of sunburn. This ingredient is found in healing SKINCEUTICALS, Cellex C and Obagi Cffectives products for skin care.

Vitamin E – Vitamin E is another antioxidant that shows to have anti-inflammatory skin. When applied topically, vitamin E has been shown to improve hydration, softness and smoothness and also provides modest photo protection. Vitamin E is found in Cellex C, Exuviance and MD Forte products.

Alpha Hydroxy Acids (AHAs) – AHAs are designed to smooth fine lines and surface wrinkles, improve skin texture and tone, to unblock and cleanse pores, improve oily skin or acne, and improve the condition skin in general. AHAs are the main ingredients found in MD Forte, TYK Young again, Super Skin and SkinScience products.

Glycolic Acid – Glycolic acid is the most active and beneficial alpha-hydroxy acids (AHAs) in skin care. Once inside the cells, the acid causes new formations of collagen to plump cells and ground substances in the skin to reduce wrinkles on the skin surface. Glycolic acid is proven highly effective in treating acne, as well as in cosmetic uses. Glycolic acid is found in products by Gly Derm, MD Forte, Z. Bigatti and Super Skin.

N-6 furfuryladenine (kinetin) – The nature-identical plant growth factor, furfuryladenine, slows the aging of plant cells and in human skin fibroblasts in vitro. This natural, anti-aging ingredient has been shown to reduce wrinkles and fine lines and is exclusively found in Kinerase creams and lotions. This is a proven alternative for people with sensitive skin or people who are sensitive to products containing retinol and vitamin C.
Copper Peptides are the latest scientific advances in skin rejuvenation. Copper has been found to naturally firm the skin, improve elasticity and reduce fine lines and wrinkles. Copper is the main ingredient in products by Neova and osmotic.

KTTKS Pal – Pal-KTTKS is an effective ingredient for reducing fine lines and wrinkles. It is to promote a smoother, younger complexion quickly, without the expensive and painful chemical peels, surgery or injections. This patented peptide solution is found in StriVectin-SD.

Against green tea extract – green tea-inflammatory and anti-growth qualities are found in many products for skin care designed to reduce the appearance of swelling, wrinkles, fine lines and large pores. Green tea is at the line of skin care Dr. Brandt, Z. Bigatti and Gly Derm products.

TNS – The biotechnology of the natural healing process of the skin has come with the first tissue repairing complex containing growth factors found in normal, healthy skin. Unlike anything else currently on the market, TNS is the next level of skin rejuvenation that delivers dramatic results for softer, smoother, younger skin. TNS is found in SkinMedica TNS Recovery Complex.

Many will make the anti-aging product is best and we always respond by saying that there is no better product. Since each person’s skin is different, the results of using anti-aging products will be different. We recommend that you consult a professional skin care before using any new product for skin care in determining your skin type, skin condition and possible sensitivity to active ingredients. Your skin care professional may recommend specific products, or you can try a few on your own based on the query. If you are not satisfied with the first product to try, try another. It is important to choose a product and a system of skin care that makes you feel 100% comfortable with the appearance of your skin.

Customers also inquire about when to expect to see the results of using anti-aging products. Again, respond by saying that the results will be different for each individual, generally due to the condition of the beings of the skin before use. However, in general, we can not say to expect a miracle, since there is no anti-aging product on the market that delivers results overnight. If you are trying to reduce the appearance of fine lines, wrinkles, dark circles, puffiness or age spots, the process is gradual and takes anywhere from 4 to 8 weeks depending on the severity of your problem areas. After allowing the products time to take effect, and follow the product instructions, you can be sure you notice a significant improvement in the appearance of your skin.

For faster results, you will have to undergo professional cosmetics procedures. Although procedures such as laser treatments, injections and dermabrasion produce the fastest, most noticeable improvements, they are all a bit uncomfortable or painful and very costly. In addition, plans for pre and post treatment required to achieve maximum results, which include the use of products for skin care, which have also proven to be safe, effective, painless and less expensive alternatives to professional procedures cosmetics.

Note that using any new product for skin care is very possible that your skin reacts to the ingredients. You may experience irritation, redness, dryness or a mild breakdown, lasting only during the first 3-5 days of use. If you experience any of these events during a long period of time, please discontinue use and consult a professional skin care. It also recommends that before using any new product for skin care, consult a professional skin care.

Article Source: http://www.articlesbase.com/advertising-articles/anti-aging-and-skin-care-why-does-the-skin-wrinkle-1306249.html

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